Endocrine Abstracts

Objectıve: Due to increased usage of imaging modalities today, incidence of adrenal incidentaloma (AI) has increased. Insulin resistance is considered as the etiopathogenic mechanism. Since both insulin and IGF-1 are capable of interacting with same receptors, we aimed to investigate whether IGF-1 has a role in development of adrenal incidentaloma.Materıals and method: 50 female patients with nonfunctional adrenal incidentaloma and 55 acromegal...

We report a patient with mycosis fungoides treated with bexarotene (Targretin), a synthetic retinoid analog with specific affinity for retinoid X receptor. This patient developed hypopituitarism characterized by hypogonadism, hypothyroidism, and hypoadrenalism. Although central hypothyroidism is a common side effect of bexarotene, central hypogonadism, and hypoadrenalism has been reported in one case. Clinicians should have high index of suspicion for hypopituitarism in patien...

Inroduction: Progressive baldness and severe hirsutism associated with granulosa cell tumor of ovaries are rare conditions in women. Reported cases are usually pubertal girls and young women. Here, we report a case of postmenopausal baldness and hirsutism due to granulosa cell tumor of the ovary.Case report: A 62 year-old woman presented with baldness and hirsutism on her face, body and back for 3 years. She had menarche at 14 years and menopause at 52 y...

Background and aim: Wrestling success depends on power, power endurance, and maximum strength, muscular endurance of short duration, flexibility as well as technique and tactical skills. Weight control and weight loss are also very important issues in the view of wrestling success. In this study, it was aimed to investigate the anthropometric features, serum lipoproteins, glucose homeostasis and leptin levels in Turkish National Senior Wrestlers and healthy sedentary males.</p...

Objectives: Mountain biking has become increasingly popular worldwide. Mountain bikes, are a common source of significant injuries including chronic overuse injuries affecting the genitourinary tract. Erectile dysfunction and infertility are some of the reported urogenital problems in male riders. Our aim was to evaluate the testicular function in male mountain bikers.Methods: Thirty male professional mountain bikers with a mean age of 23.4±2.5 year...

Introduction: Sheehan’s sydrome was known varying degrees of hypopituitarism due to postpartum ischemic necrosis by different etiologies. We report two case who are presented with pancytopenia which is unusual and rarely observed an important clinical finding associated with Sheehan’s syndrome.Case 1: A 57-year-old woman has complaints of malaise, fatigue, and dyspnea without lymphadenopatia and hepatosplenomagaly. She had excessive bleeding af...

Aim: Obstructive sleep apnea syndrome (OSAS) has been studied rarely in patients with Cushing’s syndrome. We investigated the possible association between Cushıng’s syndrome and OSAS in this study.Method: Thirty female patients with newly diagnosed Cushing’s syndrome and 30 female obese control subjects were included in this study. All the participants were evaluated by polysomnography. OSAS was defined as apneahypopnea index (AHI) of...

Aim: Thyroid papillary carcinomas smaller than 1 cm are called papillary microcarcinomas (PMC). They rarely metastasize to lymph node (LN) and distant areas. The presence of palpable lymphadenopathy at the time of diagnosis shows high risk of recurrence regardless of primary tumor size. We aimed to investigate histopathologic characteristics and recurrence frequency of thyroid PMCs with LN metastasis (LNM).Materials and methods: Thyroid PMC cases with LN...

Introduction: Osteogenesis imperfecta (OI) is a congenital, generalized connective tissue disorder characterized by severe osteoporosis and bone fragility. OI is most commonly caused by mutations in genes encoding the α-1 and α-2 chains of type I collagen or proteins involved in posttranslational modification of type I collagen. Although, no controlled studies are done, bisphosphonates are used for the treatment of OI. I.v. bisphosphonates are reported to be more eff...

Introduction: Adrenocortical carcinoma (ACC) is a rare cancer (estimated incidence, 0.7 to 2.0 cases per 1 million population per year) with a poor prognosis. Even after seemingly complete surgical resection, most patients develop recurrence within 5 years. The 5-year survival rate is <15% among patients with metastatic disease.Methods: We present the results of six patients with adrenocortical carcinoma followed in our clinic....